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Review Papers | Health & Nutrition | Indonesia | Volume 12 Issue 2, February 2023 | Rating: 5 / 10

Thrombopoietin Receptor Agonists for Treatment Thrombocytopenia in Dengue Fever

Adelina Sisilia

Abstract: Dengue fever is considered to be the most prevalent mosquito - borne viral disease worldwide and has proven to be life - threatening at times. Thrombocytopenia occurs in mild and severe cases of dengue fever. commonly observed. Severe thrombocytopenia and bleeding episodes with platelet counts well below the normal range are considered fatal consequences of dengue fever requiring appropriate and timely treatment. Thrombopoietin receptor agonists (TPO - RA) play an important role in stimulation thrombus formation. However, traditional meta - analyses have shown conflicting results efficacy of thrombopoietin receptor agonists and placebo. This review is based solely on hypotheses and articles showing a positive response to thrombopoietin receptor agonists (TPO - RA) in dengue fever after web - based searches on various search engines. Furthermore, this review highlights the need for high - quality randomized trials and meta - analyses to demonstrate the safety and efficacy of thrombopoietin receptor agonist (TPO - RA) therapy in patients with dengue - associated thrombocytopenia.

Keywords: thrombopoietin receptor agonist; dengue fever; inpatient; viral desease; thrombocytopenia

Edition: Volume 12 Issue 2, February 2023,

Pages: 910 - 911