International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Health and Medical Sciences | India | Volume 12 Issue 2, February 2023 | Rating: 5.6 / 10


Safety and Efficacy of Intermittent Fasting in Type II Diabetes Mellitus Patients on Insulin Therapy

S. Sankar Emil | P. Sahu [2] | M. Balamurali


Abstract: Objectives: To determine the safety and feasibility of 3 non-consecutive days intermittent fasting (IF) per week in type II diabetes patients already on insulin therapy. Methodology: Thirty patients each were randomized to an intermittent fasting group and control group. Dietary counseling along with continuous glucose monitoring was provided for all participants. Primary objective was to determine the change in HbA1c from baseline to 3months and secondary objective was to determine body weight reduction and reduction in daily insulin dose requirement. Results; The intermittent fasting group showed a significant reduction in HbA1c along with daily insulin dose requirement and bodyweight compared with the control group over 3months Study period (P < 0.01). No episodes of severe hypoglycemia were encountered during the study. Conclusions: Intermittent non-consecutive days fasting can be considered as a safe and reliable method to attain adequate glycemic control along with significant reduction in total daily insulin dose requirement and body weight in type II diabetes mellitus patients on insulin therapy.


Keywords: Diabetes mellitus, insulin, intermittent fasting


Edition: Volume 12 Issue 2, February 2023,


Pages: 707 - 709


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