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Research Paper | Surgery | India | Volume 12 Issue 2, February 2023
Study of Clinico Microbiological Profile of Diabetic Patients with Foot Ulcer
Dr. Anoop R | Dr. Sathish Babu N
Abstract: Background: Diabetes mellitus is a very serious disease and a major global cause of morbidity and mortality. Diabetic foot ulcers are the most common complications. Multi drug resistant pathogens with diabetic foot ulcers further complicates the treating diabetic ulcers leading to amputation. The microbiology and antibiotic resistance pattern have been evidenced to be varying with the demographic area. Hence, there is need for clinical studies at different demography in order to determine and observe the antimicrobial sensitivity pattern for early management of the DFUs. Objectives: 1) To identify the aerobic, gram negative and gram - positive bacteria causing wound infections in diabetic patients in our hospital. 2) To determine the antimicrobial susceptibility pattern of the frequently isolated Bacteria. 3) To assess risk factors responsible for causing diabetic foot ulcer in diabetic patients. Material and methods: Prospective, observational study was conducted at SRI SIDDHARTHA MEDICAL COLLEGE AND RESEARCH INSTITUTE, TUMKUR from 1st Jan 2021 to 30th Dec 2022 on 91 patients diagnosed with diabetic foot ulcers. Results: Average age of our study population was 59.1?9.5 years. The most common affected group was aged between 58 to 67 years, accounting for about 39.6% (36/91).68 (74.7%) were males and 23 (25.3%) females were present. Majority of them were suffering from DM since 5 to 10 years. There was significantly increased average blood glucose parameter. HbA1c >8 was higher. Also, significant number of patients had been found with neuropathy and loss of sensory as well as motor reflexes. Neuropathy was manifested in 61% of the population.12 (13.2%) samples did not show any growth on pus culture. Staphylococcus was yielded in 19.8% (18) samples followed by 13 (14.3%) with pseudomonas organism. We observed 100% sensitivity for cotrimoxazole, Ampicillin+sulbactum, Imipenem and meropenem followed by 92.4% were sensitive for ceftriaxone. Conclusion: Staphylococcus was the commonest organism causing diabetic foot ulcers in our study area followed by pseudomonas.100% of the organisms were sensitive forcotrimoxazole, Ampicillin+sulbactum, Imipenem and meropenem followed by 92.4% were sensitive for ceftriaxone.
Keywords: Diabetic foot ulcer, Culture sensitivity, Complication of Diabetes, Antibiotic sensitivity
Edition: Volume 12 Issue 2, February 2023,
Pages: 131 - 135