International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

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Review Papers | Medicine | India | Volume 12 Issue 11, November 2023

Anticoagulation in Internal Medicine: Finding Equilibrium in the Face of Risks and Rewards

Nallam Naga Likhita | VR Hithesh Sri Sai Reddy [4] | C. Prabhakar Raju [11]

Abstract: The use of anticoagulation therapies in internal medicine has become a cornerstone in the management of various medical conditions, ranging from atrial fibrillation and venous thromboembolism to thrombophilia and hypercoagulable states. This review paper aims to provide a comprehensive analysis of the intricate equilibrium that clinicians must navigate when employing anticoagulation strategies. The paper will delve into the pivotal role of anticoagulants in preventing thrombotic events, while concurrently addressing the inherent risks associated with these therapies, including bleeding complications. By synthesizing the latest clinical evidence and guidelines, the review will explore the evolving landscape of anticoagulation, incorporating discussions on novel oral anticoagulants, reversal agents, and personalized medicine approaches. Furthermore, the paper will shed light on the challenges encountered in specific patient populations, such as the elderly and those with comorbidities, emphasizing the need for tailored anticoagulation strategies. The intricate interplay between anticoagulation and concurrent medications, as well as the impact on patient outcomes, will be scrutinized. Additionally, the review will highlight emerging trends and advancements in anticoagulation management, including the role of biomarkers and predictive tools, as well as the integration of patient preferences into treatment decisions. Through a thorough examination of the risks and rewards associated with anticoagulation in internal medicine, this paper aims to guide clinicians in achieving a delicate balance that optimizes patient outcomes while minimizing potential adverse effects.

Keywords: Hemostasis, Bleeding Risk, Coagulation Disorders, Risk-Benefit Assessment, Stroke Prevention, Direct Oral Anticoagulants (DOACs)

Edition: Volume 12 Issue 11, November 2023,

Pages: 1556 - 1558

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