Is Diabetes Mellitus Associated with Greater Ejection Fraction Improvement After Bypass- Surgery?

Juliana Karanxha, Mirjeta Guni

Abstract: Diabetes mellitus (DM) is associated with an important risk of coronary artery disease and is known to be related with a greater risk of cardiac mortality since the Framingham studies. Diabetic patients have characteristics that differentiate them from the general population of ischemic patients: older age and associated cardiovascular risk factors, impossibility of revascularizing all arterial territories, and a greater progression of coronary artery disease. On the one hand, this means that the risk of death of diabetics without coronary artery disease is similar to that of non-diabetic patients with a history of acute myocardial infarction, and, on the other hand, that diabetics with coronary artery disease have a worse long-term prognosis than non-diabetics. Revascularization in diabetic patients with coronary artery disease remains a challenge in cardiology practice. Although clinical trials have reported the mid-term superiority of coronary artery bypass grafting (CABG) surgery over percutaneous coronary intervention in these patients, little is known about the long-term outcomes of CABG in diabetic patients compared to non-diabetics.

Keywords: Diabetes, Coronary artery bypass graft surgery, Major adverse cardiac and cerebrovascular events, acute coronary syndrome, Revascularization