Evaluation of PT and APTT in Type 2 Diabetes Mellitus Patients

Ramjeela S, Athira P R

Abstract: Diabetes mellitus is a group of metabolic disorders in which a person has high blood sugar, either because the body does not produce enough insulin or because cells do not respond to the insulin that is produced. There is evidence to show that patients with diabetes mellitus have changed hematological parameters. Prolonged hyperglycemia in diabetes mellitus patients exposes red blood cells to high glucose concentrations, which glycates proteins implicated in clotting mechanisms such as fibrinogen, prothrombin, and hemoglobin. 30 Blood samples of each type 2 diabetic mellitus patients and non-diabetic patients were collected during this period and their prothrombin time and Activated partial thromboplastin time was analyzed. From the present study there was a significant elevation of PT and APTT in Type 2 diabetes mellitus patients when compared to non-diabetic patients.

Keywords: Diabetes, FBS-Fasting Blood Sugar, PT-Prothrombin Time, APTT-Activated Partial Thromboplastin Time

How to Cite?: Ramjeela S, Athira P R, "Evaluation of PT and APTT in Type 2 Diabetes Mellitus Patients", Volume 12 Issue 11, November 2023, International Journal of Science and Research (IJSR), Pages: 598-599, https://www.ijsr.net/getabstract.php?paperid=SR231107154447, DOI: https://dx.doi.org/10.21275/SR231107154447