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Case Studies | Paediatrics | India | Volume 12 Issue 11, November 2023
Wilms Tumour with Internal Mammary Lymph Node Metastasis, Pleural Deposits and Supradiaphragmatic Nodal Involvement: A Rare Case Report
Tanvee [23] | Prarabdh Singh [3] | Sambit S Nanda [2] | Pooja Pande [2] | Soumitra Saha | Raghavesh Singh | Ashutosh Mukherji [2]
Abstract: Wilms Tumour, is the most common pediatric renal tumor, poses significant challenges in its diagnosis and management. This article presents a rare case of Wilms Tumour with internal mammary node involvement, along with pleural deposits and cardio - phrenic adenopathy. The study outlines the clinical presentation, diagnostic evaluation, and multimodal management of this unique case, highlighting the importance of adhering to the latest treatment guidelines for Wilms Tumour. Wilms Tumour, accounts for 6 of pediatric malignant diseases, primarily affects children under 15 years, with a slightly higher incidence in females. The article discusses the specific genetic mutations associated with Wilms Tumour, emphasizing its three main cell components: blastemal, stromal, and epithelial. Diagnosis involves imaging techniques such as abdominal ultrasound, CT scan, and MRI. Treatment protocols vary by region, with neoadjuvant chemotherapy and nephrectomy being common approaches. Radiotherapy is administered based on pathological staging, with an emphasis on prompt initiation post - surgery. The study underscores the impact of lymph node involvement on prognosis, especially in anaplastic histology cases, and explores the significance of lymph node density in patient outcomes. While most relapses occur within the first two years, the article emphasizes the importance of surveillance and adherence to treatment guidelines. This case report sheds light on a previously undocumented instance of Wilms Tumour involving internal mammary nodes, demonstrating the need for comprehensive research in this area. Overall, it emphasizes the complexity of Wilms Tumour management and the importance of tailoring treatment in individual cases.
Keywords: Wilms Tumour, pediatric renal tumor, internal mammary node involvement, pleural deposits, cardio - phrenic adenopathy
Edition: Volume 12 Issue 11, November 2023,
Pages: 408 - 411