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Review Papers | Biomedical Sciences | India | Volume 12 Issue 11, November 2023

A Review Article on Ankylosing Spondylitis

Ashruta Melissa Dhali

Abstract: Ankylosing spondylitis is a major form of arthritis that causes severe pain and inflammation of the spine. If not treated in earlier stages it can lead to the formation of Bamboo spine condition that includes complete fusion of the bones and accelerates the stiffness of the joints. The major contributors of the immune system that lead to ankylosing spondylitis includes cytokines and chemokines like TNF - alpha and interleukins along with human leukocyte antigen HLA - B27. This study gives an overall overview of ankylosing spondylitis as a chronic inflammatory disorder.

Keywords: Ankylosing spondylitis, spine, arthritis, immune system, inflammation

Edition: Volume 12 Issue 11, November 2023,

Pages: 356 - 359