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Research Paper | Pharmacotherapeutics | India | Volume 12 Issue 1, January 2023
Drug Utilization Study in Indoor Patients of Otorhinolaryngology Department at Tertiary Care Teaching Hospital
Abstract: Background: ENT is a medical abbreviation for ear, nose and throat. Some of the common disorders include, blocked nose or nasal discharge, ear pain, ear discharge, tender swelling behind the ear, sore throat, allergic rhinitis, otitis media and mastoiditis. Rhinitis and sinusitis are among the most common medical condition. Antibiotics are among the most common medications prescribed. As the consumption of antibiotic rises, resistance to antibiotics becomes a major threat to public health. Material & Methods: A prospective observational study conducted by Department of Pharmacology in association with Department of Otorhinolaryngology, at tertiary care teaching hospital attached to medical College. The study was performed over a period of 1 1/2 years. 650 patients were taken in study. Data was collected from inpatient of otorhinolaryngology department after the approval of institutional ethics committee obtained. Data was analyzed using general parameters like demographic profile of patient and some of the WHO indicators. Results: A total of 650 prescriptions were analysed. Out of 650 patients 411 were male and 239 were female. Mean age of the patients in study is 46.2?15.83 (Mean?SD) years. Out of 650 prescriptions, mucormycosis was the most commonillness found in 89 cases during study period followed by Chronic suppurative otitis media (CSOM) found in 71 cases which is followed by carcinoma supraglottis in 61 and sinusitisin39 cases. Prescription index was found to be 4.977. Antimicrobials were the most commonly prescribed drugs 33.79%, followed by proton pump inhibitors 14.62%, antihistaminics 13.72% and antipyretics 11.25%. Among them extended spectrum penicillin were prescribed maximally 31.75%, followed by cephalosporin 24.06%, nitroimidazole 14.27%, quinolone 11.44%, aminoglycoside 10.25%, macrolide 8.14%. Percentage of drugs from essential drug list is 68% & Non-essential drug is 32%. Percentage of drugs prescribed by generic name was 76% & brand name was 24%. Average drug cost per encounter per day for the patient was 377rs. Hospital stay range from 2-30 days with mean of 6.87days. Conclusions: We recommend Regular CMEs for the doctors at different levels to encourage prescribing by generic names and on correct writing of prescriptions may be considered. We also recommend framing strategies for drugs to be cost effective.
Keywords: Drug utilization study, Otorhinolaryngology, Antibiotics, Resistance
Edition: Volume 12 Issue 1, January 2023,
Pages: 298 - 302