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Informative Article | Dermatology | India | Volume 12 Issue 10, October 2023
Grahams Little Piccardi Lausseur Syndrome - A Rare Case Report with Review of Literature
Dr. Soundarya S [4] | Dr. Brindha J | Dr. Jayakar Thomas [6]
Abstract: Grahams Little PiccardiLassueursyndrome is a rare type of Lichenplanopilaris, presents with a triad of Scarring Alopecia in the scalp, non scarring alopecia inaxilla and pubic region, and follicular spinous papules in chest, abdomen and extremities. Commonly seen in adults between 40 and 70 yrswith female predominance of 4 times than males. Lichenplanopilaris is a rare variant of follicular lichen planusand is divided into Classical lichenplanopilaris, Frontal fibrosing alopecia and Grahams little piccardiLausseur syndrome. Lichen planopilaris shows the positive hair pull test for anagen hairs. Its etiology is unknown but mostly associated with defective cell mediated immunity. Diagnosis made by both clinical examination and histopathology. The definite treatment is notclear. Lichenplanopilaris with early stage of presentation can be treated with retinoids, Tofacitinib, Hydroxychloroquine, corticosteroids, cyclosporine, Anti Malarials and PUVA therapy. If scarring occurs, it becomes difficult to treat and only symptomatic management can be done and alopecia can not be reversed.
Keywords: Grahams Little PiccardiLassueur syndrome, Lichenplanopilaris, Follicular lichen planus, Hydroxychloroquine
Edition: Volume 12 Issue 10, October 2023,
Pages: 980 - 982