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Dissertation Chapters | Medicine | India | Volume 11 Issue 8, August 2022
The Study of Hepatoprotective Activity in Alli Chooranam (Nymphea nouchali burm.f)
Abstract: Background: Alli (Nymphea nouchali burm.f) belongs to family Nymphaeaceae has early history of traditional use, modern research has shown presence of medically active compounds such as tannins, flavonoids, nymphalin etc. Materials& methods: Ethanolic- water extract of powder of rhizome & flower evaluated for their hepato protective activity on carbon tetrachloride induced hepatotoxicity in rats. Observations: Hepato protective activity results revealed that animals pre - treated with trial drug at both doses 200 mg and 400mg significantly decreased the ALT, AST, ALP, total protein, total cholesterol. Histopathology showed that Alli (Nymphea nouchali burm.f) rhizome & flower extracts induced significant recovery from cellular damage compared to carbon tetrachloride induced group. The most significant activity was observed with Alli (Nymphea nouchali burm.f) rhizome & flower Hydroalcoholic extract at a dose of 400mg\kg. The hepatoprotective effect was statistically analyzed by ANNOVA & found to be significant. ( p <0.05).
Keywords: Alli, Nymphaea nouchali, Hepatoprotective, Siddha
Edition: Volume 11 Issue 8, August 2022,
Pages: 975 - 978