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Case Studies | Medicine Science | Indonesia | Volume 11 Issue 2, February 2022

Corticosteroid in Dengue Hemorrhagic Fever as Preventive Treatment of Severe Outcome: A Case Report

Nyoman Angga Santosa ^[2] | Diah Pradnya Paramita ^[3] | Made Wirama Diyana ^[3]

Abstract: Dengue is known as the most common vector-borne viral infection between humans by Aedes genusmosquito. Dengue has a broad spectrum of disease, ranging from asymptomatic infection to a severe systemic plasma leakage syndrome. Pathogenesis of severe dengue stillpoorly understood, one factor that is thought to cause the dreaded shock syndrome is antibody-dependent enhancement. Despite of fluid replacement therapy as the main treatment, corticosteroids usage in order to suppress immune-mediated mechanisms in DHF also expected to prevent severe outcome. Since this is still controversial, further research is still very much needed.

Keywords: dengue hemorrhagic fever, dengue shock, corticosteroids, preventive treatment

Edition: Volume 11 Issue 2, February 2022,

Pages: 1242 - 1245