The Effectivity of Ondansetron and Dexamethasone Combination as Post-Operative Nausea and Vomiting (PONV) Prophylaxis after Total Abdominal Hysterectomy and Bilateral Salpingo-Oophorectomy (TAH-BSO) Procedure at Mangusada General Hospital, Bali, Indonesia

Putu Bagus Gin Gin Pramana, Made Adi Kusuma

Abstract: Introduction: Post-operative nausea and vomiting (PONV) can be a devastating and traumatizing condition following a surgery. Risk stratification and proper prophylactic management are required to prevent PONV, particularly in high-risk patients. Case Report: A 46-year-old female with ASA II and simplified Apfel score of 3 underwent a total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH-BSO) under spinal anesthesia.4 mg of ondansetron and 5 mg of dexamethasone were administered at induction. After the procedure, the patient went stable and moved to be treated at the ward for 3 days. No nausea and vomiting were observed until the patient was discharged. Conclusion: In this case report, the combination of ondansetron and dexamethasone were sufficient to prevent PONV after TAH-BSO procedure.

Keywords: PONV, dexamethasone, ondansetron, TAH-BSO