Remineralization of Initial Enamel Caries Lesion with Self-Assembling Peptide P11-4: A Case Report

Alexander Bonchev, Radosveta Vasileva

Abstract: Self-assembling peptide (SAP) 11-4 is a biomimetic material for treatment of white spot lesions. After the application of the peptide on the lesion it diffuses into the lesion?s body which is followed by a process of self-assembly and production of three-dimensional matrix for enamel remineralization. The present case report demonstrates the ability of SAP 11-4 to induce remineralization of non-cavitated enamel lesion, evaluated by means of quantitative light-induced fluorescence (QLF) camera, ICDAS and Nyvad criteria.

Keywords: self-assembling peptide P11-4, biomimetic remineralization, enamel, white spot lesion, quantitative light-induced fluorescence