Downloads: 0 | Views: 69

Research Paper | Radiotherapy and Nuclear Medicine | Sudan | Volume 11 Issue 12, December 2022

Patient Effective Dose Estimates in 18F-FDG PET/CT Studies using OLINDA/EXM and DLP Method

Mohamed. O. M Ahmed | Sami Y. I. Awadain ^[2] | Mohamed E. M. Gar-Elnabi ^[9]

Abstract: Positron emission tomography/computed tomography (PET/CT) is the standard of care in oncologic diagnosis and staging, and patient radiation dose must be well understood. The aim of this study is to determine the specific patient effective dose in 127 patients (80 male and 47 female) with an age range of 29?90 year from a PET/CT scan using 18F-FDG.PET dose was calculated by modifying the standard reference phantoms in OLINDA/EXM software with patient-specific mass. CT dose was calculated using a computationally simpler method based on the dose length product (DLP) and k factors. And found that the mean patient effective dose from a mean injected 18F-FDG activity of 179.04 ?46.75 MBq was 2.82 ? 0.47 mSv while the mean effective dose from the CT was 8.28 ? 3.46 mSv in all patients. The five organs receiving the highest equivalent dose from 18F-FDG, in order of highest to lowest dose, were urinary bladder, heart, brain and prostate (male)/uterus (female). The results show that the effective dose is significantly lower than other studies according to lower injected activity. Radiation dosimetry using patient-specific data into dose estimates is a worthwhile effort for characterizing patient dose, and the specific dosimetric information assists in the justification of risk and optimization of PET/CT acquisition parameters.

Keywords: Radiation dosimetry PET/CT , 18F-FDG, Effective dose

Edition: Volume 11 Issue 12, December 2022,

Pages: 398 - 401