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Masters Thesis | Pharmaceutical Science | India | Volume 10 Issue 9, September 2021

Formulation and Charaterization of Clotrimazole Microemulsion for Topical Drug Delivery

Vamakshi Thaker | A. K. Singhai | Dilip Kumar Tiwari

Abstract: Clotrimazole is a broad - spectrum antimycotic drug, Candida albicans as well as other fungal infections are typically treated with this drug. ?Clinical clotrimazole seems to be a topical therapy treating tineapedis (athlete's foot), vulvo vaginal candidiasis, and oropharyngeal candidiasis.?That is a synthetic azole antimycotic. It inhibits fungal growth by decreasing the production of ergosterol. Clotrimazole has become a medication of interest for a variety of illnesses, including sickle cell anaemia, malaria, and some cancers, in addition to its antimycotic properties. It's been mixed with other molecules as well, to create clotrimazole compounds with enhanced pharmacological effectiveness, including such metals. Numerous novel pharmaceutical formulations enabling variable releases are also being developed. Clotrimazole is a well - tolerated, little - adverse drug, however certain immunocompromised individuals are developing treatment resistance. Clotrimazole's pharmaceutical chemistry, use, and pharmacology are discussed in this study.

Keywords: Antifungal drug, topical drug delivery system, clotrimazole microemulsion gel

Edition: Volume 10 Issue 9, September 2021,

Pages: 1558 - 1565