Therapy - Related Myeloid Neoplasms: A Case Report

Herman Saputra, Nicolas Xavier Ongko

Abstract: Introduction: Therapy - related myeloid neoplasms is a neoplasm that occur as a late complication of cytotoxic chemotherapy and/ or radiation therapy administered for a prior neoplastic or non - neoplastic disease. This neoplasm account for 10 - 20% of all cases of myeloid neoplasm. This paper reports a case of a 61 - year - old male with complaints of saddle - back fever for 1 month. The patient previously had a parotid gland malignancy in 2015 and had been treated with radiation therapy for 25 times. Case description: Microscopic examination shows a trephine biopsy consist of trabecular bone with a marrow spaces. Bone marrow shows a hypercellular appearance. Focus of ALIP (abnormal location of immature precursor) can be observed. The hemopoietic cells consist of myeloid, erythroid and megakaryocytic lineage. The erythroid lineage consists of normoblast. The myeloid lineage shows maturation with focus of increased blast count

Keywords: Therapy - related myeloid neoplasms, blast count, dysmegakariopoiesis

How to Cite?: Herman Saputra, Nicolas Xavier Ongko, "Therapy - Related Myeloid Neoplasms: A Case Report", Volume 10 Issue 9, September 2021, International Journal of Science and Research (IJSR), Pages: 157-160, https://www.ijsr.net/getabstract.php?paperid=SR21904121057, DOI: https://dx.doi.org/10.21275/SR21904121057

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