Downloads: 3 | Views: 32 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Case Studies | Medical Science | India | Volume 10 Issue 6, June 2021
Isolated Protein S Deficiency Leading to Cerebral Venous Sinus Thrombophlebitis in Young Male
Dr. Rahul Vemula | Dr. Sunil Kumar  | Dr. Charles Abraham | Dr. Anil Magham
Abstract: Protein S is a potent anticoagulant that downregulates thrombin formation and is a vitamin K-dependent glycoprotein which is primarily synthesized in the liver. A deficiency in this protein or decreased activity, as seen in hereditary protein S deficiency, can lead to life-threatening thrombosis. Hereditary protein S deficiency is a rare disease as listed by the National Organization for Rare Disorders (NORD). Dural venous sinus thrombosis is a rare consequence of protein S deficiency and is associated with a risk of increased morbidity and mortality.It is also known to cause venous as well as arterial thromboembolic events commonly occurring in the deep leg and pelvic veins. We are reporting a case of 17 years old male without any risk factors and comorbidities presented with headache, giddiness and diplopia who has been diagnosed with cerebral venous sinus thrombosis and associated protein s deficiency.
Keywords: proteins, cerebral venous sinus thrombosis
Edition: Volume 10 Issue 6, June 2021,
Pages: 1264 - 1266
Similar Articles with Keyword 'proteins'
Downloads: 353 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Informative Article, Medical Science, India, Volume 9 Issue 4, April 2020Pages: 1590 - 1590
Idea to Fight COVID-19
Mohammad Mamoon Jan
Research Paper, Medical Science, India, Volume 11 Issue 10, October 2022Pages: 408 - 413
A Retrospective Study of Homocysteine, Effects in Hypertensive Patients at Risk of Ischemic Stroke