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Research Paper | Pathology | India | Volume 10 Issue 1, January 2021

Histopathological Spectrum of Spinal Lesions

Dr. Jonnadula Pratima | Dr. V. Sivakota Reddy

Abstract: Introduction: Spinal lesions exhibit a wide spectrum of presentation and are classified into congenital malformations, inflammatory and infective disorders, degenerative and reactive processes, cystic lesions, vascular malformations, and neoplasms (1). Aims & Objectives: To review the histopathological spectrum of spinal lesions in relation to their site, age, sex and morphology. Materials and Methods: Our study is a retrospective study.56 biopsy specimens were included in the study over a period of 3 years from 2017 to 2019. Results: Our study shows male predominance with ratio of 1.07:1 (M:F). Among 56 specimens 48 (85.7%)were Non-Neoplastic and 8 (14.3%) were Neoplastic lesions. Pott's spine (48.2%, age 31-70yrs) is most common non-neoplastic lesion and meningioma (3.5%, age 31-40yrs)is the most common benign Neoplastic lesion observed. Discussion and Conclusion: Although the neuroimaging techniques give an idea about the location and probable diagnosis, histopathology remains the gold standard for accurate diagnosis of spinal lesions. Our study shows Pott's spine is the most common non-neoplastic spinal lesion and meningioma is the most common benign neoplastic lesion. Carcinomatous deposits are the most common malignant lesion. Similar findings were observed in Nitin M. Gadgil et al study. With respect of age and sex prediction Tuberculosis was the most common (non neoplastic) lesion in both our studies.

Keywords: Spinal lesions, Histopathologic spectrum, Pott's spine, meningioma

Edition: Volume 10 Issue 1, January 2021,

Pages: 1488 - 1490