Dyslipidemia as a Risk Factor for Preeclampsia in Pregnant Women: A Case - Control Study in Bali, Indonesia

Sawitri Ellena Juniarti, Ketut Suwiyoga, Ketut Surya Negara

Abstract: The etiology and pathogenesis of preeclampsia (PE) are still not known with certainty. Dyslipidemia and lipid profiles in pregnant women are still a polemic problem that may lead to the risk of PE in limited resources setting. This study aims to determine the role of dyslipidemia in pregnant women as a risk factor for PE. An observational with a case - control study was conducted in the delivery room of the emergency room from July to November 2020 in Bali. The Odd ratio of total cholesterol, LDL, HDL, and triglyceride levels is 0.688; 2.250; 1.250; and 2.154 respectively. Dyslipidemia may increase the risk of PE by 4 times compared with pregnant women who are not dyslipidemia (OR 4.297; 95% CI 1.413 - 13.068; p = 0.008). Triglyceride levels and dyslipidemia are indeed play role in the risk of PE. Therefore, screening of lipid serum should be used as a fixed protocol in the center of care for pregnant women to detect the risk of PE.

Keywords: dyslipidemia, lipid levels, preeclampsia, pregnant woman