Association between Serum Leptin and Anti-Mullerian Hormones in Women with Infertility in Ogbomoso Southwest Nigeria

Oke EO, Oke OF, Alao M, Oloyede TW, Smith OS, Akande JO, Ojedokun SA

Abstract: Background: One in every five women in Nigeria suffers infertility, 81.0 % of whom occurs as a result of an underlying factor. However, available data on evaluation of ovarian function as an index of fertility are largely cycle-dependent and their usefulness confounded by the use of contraceptives. This study assessed more reproducible markers of ovarian function and determines the association between serum Leptin and Anti-mullerian Hormones in Ogbomoso municipal, Southwest Nigeria. Methods: The study was age-matched case-control in a 1: 1 ratio involving 64 fertile women with informed consent and granted ethical approval. One hundred and twenty-eight women with a mean age 32.9 (5.8) years (standard deviation) were recruited for the study. Serum leptin and AMH levels were measured by Enzyme Linked Immunosorbent Assay (ELISA) method. Appropriate statistical test was used to analyse encrypted data using IBM Corp Statistical Package for Social Sciences (SPSS) TM for Windows version 23.0 (Armonk, NY: IBM Corp). The confidence level was set at 95 % and p

Keywords: Leptin, AMH, infertility, Body mass index, Obesity

How to Cite?: Oke EO, Oke OF, Alao M, Oloyede TW, Smith OS, Akande JO, Ojedokun SA, "Association between Serum Leptin and Anti-Mullerian Hormones in Women with Infertility in Ogbomoso Southwest Nigeria", Volume 9 Issue 8, August 2020, International Journal of Science and Research (IJSR), Pages: 1378-1384, https://www.ijsr.net/getabstract.php?paperid=SR20827013613, DOI: https://dx.doi.org/10.21275/SR20827013613

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