To Compare the Efficacy of Betadine, Calcium Alginate and Recombinant Epidermal Growth Factor Dressing in Chronic Diabetic Ulcers

Viswanath Nallapaneni

Abstract: Diabetic ulcer is a common problem. No standard dressing is available. We have done this study to compare the efficacy of three types of dressings in chronic diabetic foot ulcers Diabetic with non-healing for more than 3 months with saline dressing was randomized into 3 groups of 30 each. A thorough clinical examination was done to exclude ischemia and Xray to exclude osteomyelitis. Location of ulcer was noted. The wound size was measured by cutting a gauge piece to the size of the wound and placed over the graph paper. Group I received Betadine soaked gauge, II Calcium Alginate Fibers (Sorbalgon) and III Recombinant Epidermal Growth Factor gel (Eugraf 150 mcg gel) dressing minimum twice weekly, besides treatment of diabetes and co morbidities for 12 weeks. At the end of twelve weeks ulcers were assessed for healing. Calcium alginate is the significantly effective dressing in comparison to betadine and Eugraf. No significant difference in healing with Eugraf in comparison to betadine.

Keywords: Chronic diabetic ulcer, Dressing, Betadine, Calcium alginate, and Epidermal growth Factor