Evaluation for Anti-Diabetic Activity in Callus and Suspension Cultures of Lepidium sativum L.

Vibha Gupta, Nitu Singh

Abstract: The present investigation focused on the ability of callus extract for the production of pharmacologically important phytochemicals and can be used in preliminary screening of anti- hyperglycemic activity of plant species. The callus and suspension culture of Lepidium plant was established and was evaluated for anti diabetic potential by testing for inhibitor activity of alpha amylase and glucosidase enzymes. The results indicated that both seedling and callus extracts possessed considerable hyperglycemic activity and can be effective as alternatives in the treatment of diabetes.

Keywords: callus, Lepidium, anti-hyperglycemc, alpha amylase inhibitor, glucosiadase