Downloads: 73 | Views: 246
Research Paper | Pathology | India | Volume 9 Issue 12, December 2020 | Popularity: 7 / 10
Cytohistopathological Study of Central Nervous System Neoplasms
Dr. Garima Pandey, Dr. Padam Kumari Agarwal, Dr. D. K. Chhabra
Abstract: Introduction: In the neurosurgical practice, a rapid pathological diagnosis of the space occupying lesions of the nervous system is an asset and helps the neurosurgeons to plan the extent of surgery and modify it accordingly. The squash smear preparation is fairly accurate, simple and reliable tool for intraoperative diagnosis of neurosurgical biopsies. The current study was undertaken to assess the diagnostic accuracy of intraoperative cytomorphological diagnosis by squash smear technique and its correlation with histopathological diagnosis, which has been considered as ‘gold standard. ’ Aims: 1. Study of squash / imprint cytological smears of freshly excised CNS neoplasms biopsies, after staining with hematoxylin & eosin, MGG & methylene blue stain.2. To correlate with histopathological findings and study the diagnostic accuracy of squash smear vs paraffin sections. Settings and Design: Prospective, observational study. Subjects and methods: The prospective study was conducted in the Department of Pathology in collaboration with the Department of Neurosurgery of Vivekananda polyclinic and institute of medical sciences, Lucknow from May 2009 to May 2011. One hundred and two samples with symptomatic and radiologically assessed CNS neoplasms were included in the study. Intraoperative squash smears were stained by rapid methylene blue stain, hematoxylin and eosin and MGG stain. Cytological diagnoses were correlated with histopathological diagnosis which was taken as gold standard, keeping in view the clinicoradiological diagnosis as well. Diagnostic accuracy of cytosmears was calculated. Results: The overall diagnostic accuracy among the central nervous system neoplasms in our study was 93.1 % (95/102). Conclusion: Squash smear technique is a fairly accurate, simple, rapid and reliable tool for rapid intraoperative diagnosis of neurosurgical biopsies.
Keywords: intraoperative squash smears, CNS neoplasms, diagnostic accuracy
Edition: Volume 9 Issue 12, December 2020
Pages: 668 - 675
Make Sure to Disable the Pop-Up Blocker of Web Browser
Similar Articles
Downloads: 0
Case Studies, Pathology, India, Volume 11 Issue 11, November 2022
Pages: 586 - 590Role of Fine Needle Aspiration Cytology in Diagnosis of Salivary Gland Lesions
Dr. Mona Patel, Dr. Chetan Dharaiya, Dr. Jignasa Bhalodia
Downloads: 0
Research Paper, Pathology, India, Volume 12 Issue 3, March 2023
Pages: 1074 - 1077Clinical and Histomorphological Spectrum of Malignant Lesions of Thyroid in Teritiary Care Centre
Dr. Mailabathula Sundara Sikhamani
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Masters Thesis, Pathology, India, Volume 12 Issue 1, January 2023
Pages: 464 - 465PAP Smear and their Correlation with Cervical Biopsy
Dr. Divya Jyoti, Dr. Rohit Kumar, Dr. Asim Mishra, Dr. Dipti Deb Barma
Downloads: 2 | Weekly Hits: ⮙1 | Monthly Hits: ⮙2
Research Paper, Pathology, India, Volume 11 Issue 8, August 2022
Pages: 270 - 273Diagnostic Accuracy of Frozen Section in Post COVID Fungal Infections
Anusha Thangaraja, Veena Ramaswamy, Tejaswini B N, Sowmya B Uthaiah, Gaurav Medikeri
Downloads: 5 | Weekly Hits: ⮙2 | Monthly Hits: ⮙2
Review Papers, Pathology, India, Volume 12 Issue 8, August 2023
Pages: 258 - 262Correlation between the Cytological and Histopathological Analysis of Breast Lesion
Vikas Kumar, Pooja Jaiswal, Pradeep Tandon, Somil Jaiswal, Nausheen Khan