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Doctoral Thesis | Medicine | India | Volume 9 Issue 12, December 2020
A Study of Lipid Profile Inpatients of Hypothyroidism
Dr. Alpesh R. Vora | Dr. Dasare Anand Balaji
Abstract: Hypothyroidism is the most commonly encountered endocrine abnormalities in recent years. . Thyroid hormones regulate the basal energy expenditure directly or indirectly through their effect on protein, carbohydrate and lipid metabolism. Thyroid hormones have multiple effects on the regulation of lipid digestion, absorption, synthesis and catabolism. Thyroid hormones regulate the expression of enzymes involved in all steps of lipid metabolism leading to the development of qualitative and quantitative changes of lipids in thyroid dysfunction. Dyslipidaemia elevated total or low-density lipopro-tein (LDL) cholesterol levels, or low levels of high-density lipoprotein (HDL) cholesterol. Most of the patients with dyslipidaemia have primary or genetic cause and some patients have secondary factors that contribute to dyslipidemia. Thyroid dysfunction can have an important effect on lipid profile. The American Thyroid Association recommends that adults must be screened for thyroid dysfunction by the measurement of serum TSH, begin- ning at the age of 35 and every 5 years thereafter. Thyroid dysfunction is associated with increased risk of cardiovascular diseases preferentially due to altered lipid profile. As thyroid hormones affect the lipid metabolism at multiple levels we want to study the association of hypothyroidism on the lipid profiles. The present study was designed to evaluate the lipid profile levels in patients of hypothyroidism. The objectives of the study were: To evaluate alteration in lipid profile in patients of hypothyroidism. To evaluate complications occurring due to dyslipidemia in patients of hypothyroidism
Keywords: Hypothyroidism, Dyslipidemia, Serum TSH, LDL, TG, HDL
Edition: Volume 9 Issue 12, December 2020,
Pages: 184 - 188