Anthropometric and Immunological Effects of Antiretroviral Therapy in Albanian Adults

KOLPEPAJRajmonda, HARXHIArjan, XINXOSonela, NakeAdmir

Abstract: Background: Combinated antiretroviral therapy (ART) are known to gives rise CD4+ T-lymphocyte count and increased BMI (body mass index), in subjects treated for HIV/AIDS. Aim: Comparative evaluation of the CD4+ T-lymphocyte count and body mass index (BMI) at patients treated with PI (protease inhibitor) or non-PI (Nucleosid/non nucleoside transcriptase revers inhibitor). Methods. This prospective study was carry out at University Hospital Center ?Mother TERESA?, which included adults patients diagnosed with HIV / AIDS, who are treated with one of two following treatment: non nucleoside and nukleozid inhibitor (non-PI) and the other with PI, from 2011 till 2013. Were included only the patients who had data on CD4+ T-lymphocyte counts and BMI in Baseline and after, 6, 12, 24 months, in their file. The data were analized through the SPSS 17. Results. : We had studied 89 patients, which were measured BMI and CD4. Patients who where treated with PI have an significant increased of BMI compared with patients who treated with non-PI. (The technique of correlation Kendall's tau_b r = 0.123 p

Keywords: BMI, CD4+ T-lymphocyte, PI, ART, non-PI