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Research Paper | Biochemistry Science | Volume 5 Issue 6, June 2016 | Pages: 2177 - 2182 | India
Study of Serum High-Sensitivity C-Reactive Protein, Ferritin and Glycated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus
Abstract: Introduction Systemic inflammatory activity plays a key role in the pathogenesis and progression of atherosclerosis in subjects with type 2 diabetes. Hence evaluation of inflammatory novel biomarkers like high-sensitivity C-reactive protein and ferritin serves as tools for cardiovascular risk prediction. Objectives to evaluate the levels of high-sensitivity C-reactive protein (hs-CRP), ferritin & glycated haemoglobin in controls and type 2 diabetic subjects and to assess the correlations if any, between fasting serum glucose, hs-CRP, ferritin & glycated haemoglobin. Materials and Methods A total number of 100 subjects were studied, comprising of 50 controls and 50 type 2 diabetic subjects. Diabetic subjects were further divided depending upon treatment modalities. Serum levels of hs-CRP, ferritin were measured by Chemiluminescense Immunoassay. Glycated haemoglobin was measured by Nephelometry. The statistical analysis was carried out using studentt test and Karl Pearsons coefficient of correlation. Results hs-CRP, ferritin & glycated haemoglobin levels were found to be significantly increased (p
Keywords: Type 2 Diabetes Mellitus, Glycated haemoglobin, High-sensitivity C-reactive protein & Ferritin
How to Cite?: Dr. Sushma B Jagannatha, Dr. Shrikant Chandrakar, "Study of Serum High-Sensitivity C-Reactive Protein, Ferritin and Glycated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus", Volume 5 Issue 6, June 2016, International Journal of Science and Research (IJSR), Pages: 2177-2182, https://www.ijsr.net/getabstract.php?paperid=NOV164805, DOI: https://dx.doi.org/10.21275/NOV164805