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Research Paper | Hematology | Volume 5 Issue 7, July 2016 | Pages: 1668 - 1672 | Nigeria
Hepatitis B Virus Profile among Blood Donors in the Capital Territory Abuja, Nigeria
Abstract: This study was carried out to detect the prevalence of five markers of Hepatitis B virus (HBV) among prospective blood donors between the ages 18-65 years from Asokoro General Hospital Abuja, Nigeria. They were screened for Hepatitis B virus using a rapid stepwise HBV -5 panel immunoassay of Combo Cassette Manufactured by Lusys Laboratories Inc U. S. A. The overall prevalence rate of the five respective markers were HBsAg 18 (17.5), HBeAg 2 (1.9), HBsAb 18 (17.5), HBeAb 25 (24.5), and HBc 63 (61.2). Donors aged (30-40) years had the highest prevalence rate of hepatitis B virus infection compared to age groups 21-30 years and 41 years and above. Statistically, there was significant relationship between the prevalence rate of HBsAg and frequency of donation at p (0.05). Most of the samples that tested negative for HBsAg were found to be positive for other markers especially anti-HBc IgG and IgM). While anti- HBc IgG is useful for the detection of chronic HBV infection, anti-HBc IgM is useful in detecting recent infection of HBV. Thus, this study has showed that screening for HBsAg alone may not be sufficient for the diagnosis of hepatitis B virus infection.
Keywords: Hepatitis B, Blood donors, Serological markers Hepatitis B, Blood donors, Serological markers Hepatitis B, Blood donors, Serological markers Hepatitis B, BloodDonors, Serological markers
How to Cite?: Agbesor. N. Innocent, Amala Smart E., Zaccheaus. A. Jeremiah, "Hepatitis B Virus Profile among Blood Donors in the Capital Territory Abuja, Nigeria", Volume 5 Issue 7, July 2016, International Journal of Science and Research (IJSR), Pages: 1668-1672, https://www.ijsr.net/getabstract.php?paperid=NOV163915, DOI: https://dx.doi.org/10.21275/NOV163915