International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

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Research Paper | Medicine Science | India | Volume 5 Issue 5, May 2016

Relationship between Malaria and ABO Blood Group Types

Sharana Hegde | Ruchi Sinha | Shrijeet Chakraborti | Lavnish Ojha

Abstract: Introduction There is a paucity of studies on the relationship between ABO blood group and its influence on malarial infection. This study was undertaken to study the relationship of severity of malaria with blood groups and to evaluate if ABO blood groups show differential susceptibility to falciparum malaria. Methods In 200 malaria positive patients, blood group analysis was done. Patients with atleast one of the following complications were considered complicated malaria cases, ie cerebral malaria, severe anemia, circulatory collapse, jaundice, hematuria, bleeding manifestations, acute respiratory distress syndrome, death. Results Vivax malaria (75.5 %) and blood group O (43 %) were the commonest amongst the cases. No significant relationship was present between blood groups and type of infection, parasite load vs blood groups, and complicated cases vs parasite load. Uncomplicated (62 %) cases were more than complicated (31 %) cases. Blood group O dominated among complicated (37.9 %) and uncomplicated (45.65 %) cases. No significant correlation was present between blood groups and distribution of complicated cases, and between complicated falciparum cases and blood groups. Seven cases of mixed malaria had blood group A and O. Among A blood group, 57.1 % of the mixed malaria cases had complications, whereas in O blood group only 14.3 % had complications. There was a statistically significant relation between complicated mixed malaria cases and blood groups, with blood group A being more prone to complications. (X2=15.131, P=0.019). Conclusions Blood group O was the dominant blood type in both complicated and uncomplicated malaria cases. Blood group A cases were more prone to severe mixed malaria infections while, blood group O had a favorable clinical outcome.

Keywords: Blood group, Plasmodium falciparum, Plasmodium vivax, Mixed malaria, Complicated malaria

Edition: Volume 5 Issue 5, May 2016,

Pages: 1041 - 1044

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