Activity Patterns of Cell Free Supernatant of Antagonistic Microbial Strains in Rodents Host-Parasite Systems

Sushil K. Upadhyay

Abstract: Helminthes parasites are the major consequence in homeotherms and play very significant economic values for health, bioecology and zoonoses. The microbial interactions in the terrestrial ecosystem were demonstrated to be of antagonistic potential in relation to parasitic nematodes in rodent hosts, Rattus rattus. The endoparasitic roundworms of genus Pseudaspidodera harbored gram positive streptobacilli bacteria, Actinomyces on its body surface. The bacteria residing on the body surface of rodents gut nematodes, provides a very good medium for better survival of roundworms by their microhabitat specific activities. The antagonistic activity of the positive coccii, Staphyllococcus bacteria proved in vitro in the present investigation. The antagonistic bacterial strains were recovered from soil of giant fresh water prawn, Macrobrachium rosenbergii fisheries ponds in eastern regions of Uttar Pradesh, India. The growth and patterns of inhibitions by microbial metabolites exhibited interesting variations which explained characteristic interactions of antagonistic vs susceptible bacteria. Thus allelopathic correlations and interaction of antagonistic microbial metabolites reduced the population of Actinomyces bacterial strains, in turn caused unfavorable environment for roundworms, Pseudaspidodera cordinae in rodents gut. Therefore, infestation and establishment of helminthes in rodents became critical and hosts experienced healthier. So that the recovered bacterial strains can be apply as probiotic agents in terrestrial host-parasite systems.

Keywords: Antagonism, Staphyllococcus, Actinomyces, Probiotics, Rattus rattus, Macrobrachium rosenbergii, Host-parasite systems