International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064

Downloads: 115 | Views: 152

Research Paper | Chemistry | India | Volume 5 Issue 3, March 2016

RP-HPLC Method Development and Validation for the Analysis of Pharmaceutical Drugs ? Paracetamol

Dr. Bhaskarrav N. Makwana [2]

Abstract: A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of PARACETAMOL. Isocratic elution at a flow rate of 1.0 ml /min was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of Acetonitrile 0.1M Acetic Acid 5050 (v/v). The UV detection wavelength was at 210 nm. Linearity was observed in concentration range of 100-140 mg/ml. The retention time for Paracetamol was 3.0 min. The method was validated as per the ICH guidelines. The proposed method can be successfully applied for the estimation of Paracetamol.

Keywords: Paracetamol, Method Development, Validation, 210nm

Edition: Volume 5 Issue 3, March 2016,

Pages: 2093 - 2095

How to Download this Article?

Type Your Email Address below to Receive the Article PDF Link

Verification Code will appear in 2 Seconds ... Wait