Country not found in response RP-HPLC Method Development and Validation for the Analysis of Pharmaceutical Drugs ? Paracetamol
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 115 | Views: 324

Research Paper | Chemistry | India | Volume 5 Issue 3, March 2016 | Popularity: 6.4 / 10


     

RP-HPLC Method Development and Validation for the Analysis of Pharmaceutical Drugs ? Paracetamol

Dr. Bhaskarrav N. Makwana


Abstract: A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of PARACETAMOL. Isocratic elution at a flow rate of 1.0 ml /min was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of Acetonitrile 0.1M Acetic Acid 5050 (v/v). The UV detection wavelength was at 210 nm. Linearity was observed in concentration range of 100-140 mg/ml. The retention time for Paracetamol was 3.0 min. The method was validated as per the ICH guidelines. The proposed method can be successfully applied for the estimation of Paracetamol.


Keywords: Paracetamol, Method Development, Validation, 210nm


Edition: Volume 5 Issue 3, March 2016


Pages: 2093 - 2095


DOI: https://www.doi.org/10.21275/NOV162367


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Dr. Bhaskarrav N. Makwana, "RP-HPLC Method Development and Validation for the Analysis of Pharmaceutical Drugs ? Paracetamol", International Journal of Science and Research (IJSR), Volume 5 Issue 3, March 2016, pp. 2093-2095, https://www.ijsr.net/getabstract.php?paperid=NOV162367, DOI: https://www.doi.org/10.21275/NOV162367

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