RP-HPLC Method Development and Validation for the Analysis of Pharmaceutical Drugs ? Paracetamol
International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 115 | Views: 280

Research Paper | Chemistry | India | Volume 5 Issue 3, March 2016 | Popularity: 6.4 / 10


     

RP-HPLC Method Development and Validation for the Analysis of Pharmaceutical Drugs ? Paracetamol

Dr. Bhaskarrav N. Makwana


Abstract: A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of PARACETAMOL. Isocratic elution at a flow rate of 1.0 ml /min was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of Acetonitrile 0.1M Acetic Acid 5050 (v/v). The UV detection wavelength was at 210 nm. Linearity was observed in concentration range of 100-140 mg/ml. The retention time for Paracetamol was 3.0 min. The method was validated as per the ICH guidelines. The proposed method can be successfully applied for the estimation of Paracetamol.


Keywords: Paracetamol, Method Development, Validation, 210nm


Edition: Volume 5 Issue 3, March 2016


Pages: 2093 - 2095


DOI: https://www.doi.org/10.21275/NOV162367



Make Sure to Disable the Pop-Up Blocker of Web Browser




Text copied to Clipboard!
Dr. Bhaskarrav N. Makwana, "RP-HPLC Method Development and Validation for the Analysis of Pharmaceutical Drugs ? Paracetamol", International Journal of Science and Research (IJSR), Volume 5 Issue 3, March 2016, pp. 2093-2095, https://www.ijsr.net/getabstract.php?paperid=NOV162367, DOI: https://www.doi.org/10.21275/NOV162367

Similar Articles

Downloads: 1

Research Paper, Chemistry, India, Volume 11 Issue 2, February 2022

Pages: 662 - 670

3D QSAR Analysis of a Set of Pneumocystis carinii DHFR Inhibitors through Pharmacophore Generation Approach

Ruchi Mishra

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Chemistry, India, Volume 11 Issue 5, May 2022

Pages: 1689 - 1692

Analytical Method Development and Validation for Larcenidepin and its Stages by High Performance Liquid Chromatography

Virendra Sopan Pathare

Share this Article

Downloads: 2 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Chemistry, India, Volume 11 Issue 2, February 2022

Pages: 655 - 661

Determination of Chloride, Sulfate, Trifluoroacetic acid, Phosphate, Sodium and Ammonium from Semaglutide by Ion Chromatography

Chetan Chavan, Chanakya Thaker, Chetan Chaudhari

Share this Article

Downloads: 2 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper, Chemistry, India, Volume 11 Issue 5, May 2022

Pages: 1852 - 1855

Analytical Method Development and Validation for Baclofen and its Stages by High Performance Liquid Chromatography

Pathare Virendra Sopan

Share this Article

Downloads: 16 | Weekly Hits: ⮙1 | Monthly Hits: ⮙4

Research Paper, Chemistry, India, Volume 13 Issue 8, August 2024

Pages: 1846 - 1854

Development and Validation of Analytical Method for Simultaneous Estimation of Dapagliflozin Propanediol Monohydrate and Sitagliptin Phosphate Monohydrate in Tablet Dosage Form

Axita Parmar, Priyanka Patil, Krishna Soni, Dr Chainesh Shah, Dr Umesh Upadhyay

Share this Article



Top