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Egypt | Chemistry | Volume 5 Issue 1, January 2016 | Pages: 297 - 302
Radiation Synthesis and Characterization of Cholesterol Molecularly Imprinted Polymer of Crosslinked Hydroxyethyl Methacrylate
Abstract: Cholesterol-imprinted poly hydroxyethyl methacrylate (MIP) and non-imprinted polyhydroxyethyl methacrylate (NIP) have been prepared via polymerization by gamma radiation. The functional structure of the imprinted and non-imprinted polymers were characterized by Fourier Transform Infrared spectroscopy (FT-IR), the spectrum showed that the HEMA interacts with cholesterol through H-bonds. The surface morphology of NIP and MIP were investigated by scanning electron microscope (SEM) and the MIP image appeared as a rough surface, while NIP had no pores. The specificity of MIP to interact with the print molecular was studied cholesterol and the results showed a higher cholesterol adsorption by MIP than that by NIP. This work approaches to design robust MIP to mimic natural recognition entities as adsorbed materials of cholesterol.
Keywords: Molecular imprinted polymers, NIP, HEMA, Cholesterol and Gamma Radiation
How to Cite?: EL-Sayed A. Hegazy, Gilane M. Sabry, Magda K. Ezz, H. Kamal, S. Lotfy, Somaya Zakaria Mansour, Dina Hassan Eissa, "Radiation Synthesis and Characterization of Cholesterol Molecularly Imprinted Polymer of Crosslinked Hydroxyethyl Methacrylate", Volume 5 Issue 1, January 2016, International Journal of Science and Research (IJSR), Pages: 297-302, https://www.ijsr.net/getabstract.php?paperid=NOV152733, DOI: https://dx.doi.org/10.21275/NOV152733