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Research Paper | Chemistry | Egypt | Volume 5 Issue 1, January 2016
Radiation Synthesis and Characterization of Cholesterol Molecularly Imprinted Polymer of Crosslinked Hydroxyethyl Methacrylate
EL-Sayed A. Hegazy | Gilane M. Sabry | Magda K. Ezz | H. Kamal | S. Lotfy | Somaya Zakaria Mansour | Dina Hassan Eissa
Abstract: Cholesterol-imprinted poly hydroxyethyl methacrylate (MIP) and non-imprinted polyhydroxyethyl methacrylate (NIP) have been prepared via polymerization by gamma radiation. The functional structure of the imprinted and non-imprinted polymers were characterized by Fourier Transform Infrared spectroscopy (FT-IR), the spectrum showed that the HEMA interacts with cholesterol through H-bonds. The surface morphology of NIP and MIP were investigated by scanning electron microscope (SEM) and the MIP image appeared as a rough surface, while NIP had no pores. The specificity of MIP to interact with the print molecular was studied cholesterol and the results showed a higher cholesterol adsorption by MIP than that by NIP. This work approaches to design robust MIP to mimic natural recognition entities as adsorbed materials of cholesterol.
Keywords: Molecular imprinted polymers, NIP, HEMA, Cholesterol and Gamma Radiation
Edition: Volume 5 Issue 1, January 2016,
Pages: 297 - 302