Evaluation of Some Non Invasive Predictors for Presence of Esophageal Varices in Patients with Compensated HCV Positive Cirrhosis

Hoda AbdEl-Aziz Elhady MD, Ashraf A. Hammam MD, Sahar A. Elnimr MD, Asmaa M. H. Osh MD

Abstract: A B S T R A C T Background The current guidelines recommend the screening of all cirrhotic patients by endoscopy for esophageal varices (EV), but repeated endoscopic examinations are unpleasant for patients and have a high cost impact and burden on endoscopic units. Recognition of non-invasive predictors of EV will allow upper gastrointestinal tract (GIT) endoscopy to be carried out only in a selected group of patients, thus avoid unnecessary intervention and at the same time not to miss patients at risk of bleeding. Aim the aim of this study was to evaluate the validity of three non- invasive parameters in the prediction of esophageal varices in patients with compensated hepatitis C virus (HCV) +ve liver cirrhosis namely insulin resistance, platelet count/spleen diameter ratio and right liver lobe diameter/albumin ratio. Patients and Methods This prospective study included one hundred non-diabetic, non-obese patients with Child A HCV induced cirrhosis. All studied patients underwent a detailed history, thorough physical examination, biochemical workup, upper gastrointestinal endoscopy and abdominal ultrasound. Insulin resistance (IR) by the homeostasis model assessment (HOMA), the platelet count/spleen diameter ratio and the right liver lobe diameter/albumin ratio for all patients were calculated. Results The prevalence of esophageal varices in Child A HCV +ve cirrhosis were high. The three predictors demonstrated a high statistically significant correlation with the presence and grade of esophageal varices (P values

Keywords: Esophageal varices, HCV +ve liver cirrhosis, Non invasive predictors, Evaluation, Compensated

How to Cite?: Hoda AbdEl-Aziz Elhady MD, Ashraf A. Hammam MD, Sahar A. Elnimr MD, Asmaa M. H. Osh MD, "Evaluation of Some Non Invasive Predictors for Presence of Esophageal Varices in Patients with Compensated HCV Positive Cirrhosis", Volume 5 Issue 1, January 2016, International Journal of Science and Research (IJSR), Pages: 461-469, https://www.ijsr.net/getabstract.php?paperid=NOV152725, DOI: https://dx.doi.org/10.21275/NOV152725

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