International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Medical Surgical | Volume 4 Issue 11, November 2015 | Pages: 1795 - 1799 | Indonesia


Protector Effect of Curcumin against the Nasal Mucosa after Cigarettes Smoke Exposure

Abdul Qadar Punagi, Sutji Pratiwi Rahardjo, Ervina Mariani, Upik Miskad

Abstract: Introduction The level of cigarette consumption in Indonesia is very high and causes the magnitude of the danger that may result in respiratory and cancer risk. This study aims to determine the effectiveness of curcumin in improving nasal mucosa of Wistar mice as a result of exposure to cigarette smoke. Materials and methods The study was conducted from March to August 2015. The study was conducted in animal experiments laboratory and research unit of the Medical Faculty of Hasanuddin University. The study sample of 15 Wistar mice were divided into three groups the provision of cigarette smoke, the group with the provision of smoke and curcumin 200mg, the group with the provision of smoke and curcumin 400mg. Results Results of the study group I showed that the changes in the nasal mucosa of Wistar mice in the form of inflammation, erosion, epithelial disarrangement and epithelial metaplasia. Group II and group III showed a significant difference in the degree of inflammation in group (p

Keywords: Cigarette smoke, Curcumin, Nasal mucosa

How to Cite?: Abdul Qadar Punagi, Sutji Pratiwi Rahardjo, Ervina Mariani, Upik Miskad, "Protector Effect of Curcumin against the Nasal Mucosa after Cigarettes Smoke Exposure", Volume 4 Issue 11, November 2015, International Journal of Science and Research (IJSR), Pages: 1795-1799, https://www.ijsr.net/getabstract.php?paperid=NOV151575, DOI: https://dx.doi.org/10.21275/NOV151575

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