Downloads: 0
Research Paper | Medical Science | Volume 15 Issue 6, June 2026 | Pages: 1019 - 1021 | India
Association of Metabolic Syndrome with Non-Alcoholic Fatty Liver Disease in Adult Patients Attending a Tertiary Care Hospital: A Cross-Sectional Study
Abstract: Background and Objective: Non-Alcoholic Fatty Liver Disease (NAFLD) is emerging as the most common chronic liver disease worldwide and is closely associated with obesity, insulin resistance, type 2 diabetes mellitus, dyslipidemia, and metabolic syndrome. Our objective was to evaluate the association between metabolic syndrome and NAFLD among adult patients attending a tertiary care hospital. Methods: A hospital-based cross-sectional study was conducted in the Department of General Medicine, Index Medical College Hospital & Research Centre, Indore over 12 months. A total of 140 adult patients were enrolled and divided into NAFLD and non-NAFLD groups based on ultrasonographic assessment. Metabolic syndrome was diagnosed using Modified NCEP ATP III criteria. Results: Of 140 participants, 92 (65.7%) had NAFLD. Metabolic syndrome was significantly more prevalent among NAFLD patients than non-NAFLD patients (77.2% vs 31.3%; χ2=28.4, p<0.001). NAFLD patients had significantly higher BMI and waist circumference (p<0.001). Central obesity (82.6%), hyperglycemia (66.3%) and hypertension (63.0%) were the commonest components among NAFLD patients, and the prevalence of metabolic syndrome rose with increasing NAFLD grade, from 64.3% in Grade I to 93.3% in Grade III (p=0.004). Conclusion: Metabolic syndrome is strongly and significantly associated with the presence and severity of NAFLD. Early screening of high-risk individuals may reduce disease progression and long-term hepatic complications.
Keywords: NAFLD, Metabolic Syndrome, Obesity, Insulin Resistance, Fatty Liver, Type 2 Diabetes Mellitus
How to Cite?: Dr. Seema Yadav, Dr. Pujasha Patidar, Dr. Patel Dev Manish, Dr. Anshul Mehta, Dr. Sudhir Mourya, "Association of Metabolic Syndrome with Non-Alcoholic Fatty Liver Disease in Adult Patients Attending a Tertiary Care Hospital: A Cross-Sectional Study", Volume 15 Issue 6, June 2026, International Journal of Science and Research (IJSR), Pages: 1019-1021, https://www.ijsr.net/getabstract.php?paperid=MR26619143657, DOI: https://dx.doi.org/10.21275/MR26619143657