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Research Paper | Anaesthesiology | Volume 15 Issue 5, May 2026 | Pages: 12 - 13 | India
Comparison of Intrathecal Dexmedetomidine and Fentanyl as Adjuvants to 0.5% Hyperbaric Bupivacaine in Spinal Anaesthesia for Post Traumatic Femur Fracture Repair Surgeries
Abstract: Background: Hyperbaric bupivacaine is widely used for spinal anesthesia in orthopedic trauma surgery, but its duration is limited. Intrathecal adjuvants such as fentanyl and dexmedetomidine are used to improve block quality and extend postoperative analgesia. Aim: To compare the efficacy and safety of dexmedetomidine versus fentanyl as intrathecal adjuvants to 0.5% hyperbaric bupivacaine in patients undergoing post traumatic femur fracture repair. Methods: A retrospective comparative study was conducted on 30 ASA I?II adults undergoing intramedullary nailing for post traumatic femur fractures. Group D received intrathecal dexmedetomidine (3 μg) with hyperbaric bupivacaine, and Group F received intrathecal fentanyl (20 μg). Sensory and motor block onset, block duration, analgesic requirement, hemodynamics, and adverse effects were assessed. Results: Dexmedetomidine provided a faster onset of sensory block and significantly prolonged sensory and motor block duration compared with fentanyl. Postoperative analgesia lasted longer in Group D. Hemodynamics were more stable with dexmedetomidine, while fentanyl produced more opioid related side effects such as pruritus and nausea. No major complications occurred. Conclusion: Dexmedetomidine is a superior intrathecal adjuvant to fentanyl for spinal anesthesia in femur fracture surgery, offering prolonged anesthesia, extended analgesia, greater hemodynamic stability, and fewer adverse effects.
Keywords: spinal anesthesia; dexmedetomidine; fentanyl; hyperbaric bupivacaine; postoperative analgesia; femur fracture
How to Cite?: Dr. Manasi Rajeev, Dr. Jessy Vennel, Dr. Deepika Sathe, "Comparison of Intrathecal Dexmedetomidine and Fentanyl as Adjuvants to 0.5% Hyperbaric Bupivacaine in Spinal Anaesthesia for Post Traumatic Femur Fracture Repair Surgeries", Volume 15 Issue 5, May 2026, International Journal of Science and Research (IJSR), Pages: 12-13, https://www.ijsr.net/getabstract.php?paperid=MR26430182456, DOI: https://dx.dx.doi.org/10.21275/MR26430182456