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Original Research | Orthopaedic Surgery | Volume 15 Issue 4, April 2026 | Pages: 1824 - 1827 | India
Evaluating the Effectiveness of Intra-Articular Triamcinolone Injections in Patients with Knee Osteoarthritis: An Observational Study
Abstract: Background: Knee osteoarthritis (OA) is a prevalent condition that leads to pain, stiffness, and functional impairment. Intra-articular corticosteroid injections, such as triamcinolone, are commonly used to manage symptoms in knee OA patients. While several studies have explored the effectiveness of these injections, this observational study aimed to evaluate the real-world outcomes of triamcinolone injections in knee OA management. Methods: This observational study included 60 patients with moderate to severe knee OA who received a single intra-articular injection of 40 mg of triamcinolone as part of their routine clinical care. Patients were followed for 12 weeks, with assessments of pain relief and knee function at baseline, 4, 8, and 12 weeks post-injection. Pain was measured using the Visual Analog Scale (VAS), and knee function was evaluated using the WOMAC Osteoarthritis Index. Adverse effects were also monitored during the study period. Statistical analysis was conducted using paired t-tests to compare outcomes at follow-up time points. Results: Participants demonstrated significant improvements in both pain and function. The baseline mean VAS score for pain was 7.4, decreasing to 4.1 at 4 weeks, 3.8 at 8 weeks, and 4.0 at 12 weeks (p<0.05 for all). The baseline WOMAC physical function score was 40.2, improving to 27.5 at 4 weeks, 24.3 at 8 weeks, and 25.1 at 12 weeks (p<0.05 for all). No serious adverse effects were reported, although 5 patients experienced mild transient swelling, and 3 reported brief flare-ups of pain. Conclusion: Intra-articular triamcinolone injections provide significant short-term pain relief and functional improvement for patients with knee OA. The results are consistent with existing literature, suggesting that triamcinolone can be an effective and well-tolerated treatment for managing knee OA symptoms. Future randomized controlled trials with long-term follow-up are needed to further validate these findings.
Keywords: Knee osteoarthritis, Triamcinolone injection, Pain relief, Joint function, Corticosteroid therapy
How to Cite?: Dr. Sunil P. Handralmath, Dr. Sanket Vaman Chaware, Dr. Yogesh Mudholkar, "Evaluating the Effectiveness of Intra-Articular Triamcinolone Injections in Patients with Knee Osteoarthritis: An Observational Study", Volume 15 Issue 4, April 2026, International Journal of Science and Research (IJSR), Pages: 1824-1827, https://www.ijsr.net/getabstract.php?paperid=MR26428160041, DOI: https://dx.dx.doi.org/10.21275/MR26428160041