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Comparative Studies | Pathology | Volume 15 Issue 3, March 2026 | Pages: 931 - 932 | India
Role of Platelet Indices as Predictors of Postpartum Haemorrhage: A Case-Control Study from a Tertiary Care Hospital
Abstract: Background: Postpartum haemorrhage (PPH) remains one of the leading causes of maternal morbidity and mortality worldwide. Early identification of women at risk is essential for timely prevention and management. Platelet indices such as mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT), and platelet large cell ratio (PLCR) are readily available parameters from routine complete blood count testing and may serve as potential predictors of PPH. Aim: To evaluate the role of platelet indices in predicting postpartum haemorrhage and assess their usefulness as potential biomarkers for risk stratification. Methods: A hospital-based case?control study was conducted in the Department of Obstetrics and Gynecology in collaboration with the Department of Pathology at a tertiary care hospital in Hyderabad. A total of 200 postpartum women were included, comprising 100 cases (PPH) and 100 controls (without PPH). Pre-delivery platelet parameters including platelet count, MPV, PDW, PCT, and PLCR were obtained from complete blood count reports. Statistical analysis was performed using SPSS software. Comparisons between groups were made using Student's t-test and Chi-square test. Receiver operating characteristic (ROC) curves and logistic regression analysis were used to evaluate predictive performance. Results: Women with postpartum haemorrhage demonstrated significantly lower platelet count and plateletcrit and significantly higher MPV, PDW, and PLCR compared to controls (p < 0.001). Platelet indices also showed a significant association with severity of PPH. ROC analysis revealed that MPV had the highest predictive accuracy (AUC = 0.86), followed by PDW and PLCR. Multivariable logistic regression analysis identified low platelet count, elevated MPV, elevated PDW, reduced PCT, elevated PLCR, and low hemoglobin as independent predictors of postpartum haemorrhage. Conclusion: Platelet indices, particularly MPV, are significantly associated with postpartum haemorrhage and may serve as simple, inexpensive, and readily available biomarkers for early identification of high-risk women.
Keywords: Postpartum haemorrhage, Platelet indices, Mean platelet volume, Platelet distribution width, Plateletcrit, PLCR
How to Cite?: Dr. MD Juberia Tabassum, Dr. Mohmed Chand Moula, Dr. Naval Kishore, "Role of Platelet Indices as Predictors of Postpartum Haemorrhage: A Case-Control Study from a Tertiary Care Hospital", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 931-932, https://www.ijsr.net/getabstract.php?paperid=MR26315133656, DOI: https://dx.dx.doi.org/10.21275/MR26315133656