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Case Studies | Pediatrics | Volume 15 Issue 3, March 2026 | Pages: 23 - 25 | India
A Case study on Pituitary Hypoplasia in a 5 Year Female Child
Abstract: Background: Pituitary hypoplasia is a rare congenital anomaly characterised by underdevelopment of the pituitary gland, resulting in partial or complete hormone deficiencies. It may present as isolated growth hormone deficiency or as multiple pituitary hormone deficiencies. Early diagnosis through careful clinical evaluation, hormonal assessment, and magnetic resonance imaging of the hypothalamic?pituitary axis is essential for timely management. Hormone replacement therapy and multidisciplinary care significantly improve growth, metabolic function, and developmental outcomes. Objective: This review summarises the clinical profile, diagnostic modalities and treatment outcomes of pituitary hypoplasia in paediatric population. Methods: Clinical evaluation, hormonal investigations, bone age assessment, and magnetic resonance imaging were performed to establish the diagnosis. We report a case of isolated growth hormone deficiency secondary to pituitary hypoplasia in a five-year-old female presenting with short stature. Results: Isolated growth hormone deficiency. Bone age was delayed compared to chronological age. Magnetic resonance imaging of the brain demonstrated a hypo plastic anterior pituitary gland, confirming the structural basis of the deficiency. Child was initiated on appropriate hormone replacement therapy with planned regular endocrine follow-up. Conclusion: Early recognition of pituitary hypoplasia in children with short stature is essential. Timely diagnosis and hormone therapy can significantly improve growth outcomes.
Keywords: Pituitary hypoplasia, Hypopituitarism, Growth hormone deficiency, Paediatric endocrinology
How to Cite?: Dr. Prachi Shukla, Dr. Saiprasad Tilagul, Dr. Payal Jalandhara, Dr. Sangita Trivedi, "A Case study on Pituitary Hypoplasia in a 5 Year Female Child", Volume 15 Issue 3, March 2026, International Journal of Science and Research (IJSR), Pages: 23-25, https://www.ijsr.net/getabstract.php?paperid=MR26301135315, DOI: https://dx.dx.doi.org/10.21275/MR26301135315