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New Innovation and Idea | Diabetology | Volume 15 Issue 2, February 2026 | Pages: 1410 - 1420 | India
Lipid and Apolipoprotein Metabolic Homeostasis by Scientifically Targeting Interventional Therapy with Quality & Quantity of HDLc & Chylomicron Produced in GI Tract & HDLc and VLDLc Produced in Liver Cells & Giving Importance to Daily Post Prandial Exercise in Each Meal for Best Nutritional Management of Dietary Food to Avoid Ectopic Fat Deposits from Prandial Sugar
Abstract: Lipid, the mother of all metabolic and immunological disorders, even sugar without a part to lipid fats or transfer to 14 and 16 saturated fatty acids have limited or absolute no effect on metabolic or immunological disorders. Sugar related disorders arise only when cells and organs deposits advanced glycation end products inside the cell or organs making it dysfunctional in due course of time and irreversible accumulation of advance glycation end products of lipid and amino acids causing permanent deposits inside cell and producing oxidative stress and ultimate death of the cell. Sugar may periodically produce osmolar effect due to hyperglycemia and Ketoacidosis due to insufficient supply of insulin in blood. Post prandial nutritional containing esters of fatty acids in triglycerides and LDLc play a major part in management of metabolic diseases according to their saturated and unsaturated (both mono and poly) fatty acid contents producing different types of metabolic disorders. And play a vital role in maintaining metabolic homeostasis and disorders. The gastrointestinal tract serves as the primary control point for nutrient absorption, with glucose being a key factor in the development of ectopic fat deposits, particularly in the liver & pancreas. Unregulated glucose absorption leads to inflammatory conditions, contributing to metabolic disorders like fatty liver disease and atherosclerosis. Effective glucose management strategies, including inhibiting specific transporters and performing post meal exercises, can help control postprandial glucose levels, reduce ectopic fat deposits, and maintain overall metabolic health. This article explores various management approaches aimed at sustaining calorie balance and preventing metabolic dysfunctions.
Keywords: Post prandial moderate intensive exercise, 3 doses of prior pre-prandial nutrition (Break-fast, Lunch and Dinner), brain hypothalamus arcuate nucleus, Metabolic homeostasis, calorie, postprandial glucose, metabolic disorders, ectopic fats, glucose transporters, SGLT1, Glut 2. GLP1R, Insulin RA, GIPRA insulin RA, GIPRA, triglyceride LDLc.
How to Cite?: Dr. Bansi Saboo, Dr. L Srenevas Murthy, Dr. Shilpa Varma, Dr. Mridul Bera, Dr. Mahendra Prasad Tripathy, Dr. Bijay Ketan Dash, Dr. Bharat Panigrahi, Dr. Rabindra Ku. Nayak, Dr. Pratap Ku. Pradhan, Dr. Susil Ku. Mohanty, "Lipid and Apolipoprotein Metabolic Homeostasis by Scientifically Targeting Interventional Therapy with Quality & Quantity of HDLc & Chylomicron Produced in GI Tract & HDLc and VLDLc Produced in Liver Cells & Giving Importance to Daily Post Prandial Exercise in Each Meal for Best Nutritional Management of Dietary Food to Avoid Ectopic Fat Deposits from Prandial Sugar", Volume 15 Issue 2, February 2026, International Journal of Science and Research (IJSR), Pages: 1410-1420, https://www.ijsr.net/getabstract.php?paperid=MR26219233720, DOI: https://dx.dx.doi.org/10.21275/MR26219233720