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Research Paper | Medical Microbiology | India | Volume 14 Issue 1, January 2025 | Popularity: 5.4 / 10
Recent Trends in LSCS Surgical Site Infections and Therapeutic Strategies
Dr. Winston Rose Cr, Dr. Deepa S, Dr. Amrutha Kumari B
Abstract: Introduction: In obstetrics there has been a sharp rise in lower segment caesarean section (LSCS) over last 30 years in view of improving maternal and perinatal outcome. With this, there has been a definitive increase of postpartum infections. So, it?s necessary to identify the recent trends in resistance shown by MDR bugs and therapeutic strategies to overcome that and to make relevant health recommendations aimed at preventing, controlling, or managing caesarean section wound infections. Materials and Methods: A prospective study was conducted among 88 patients with LSCS wound infections during the period of February 2023 to November 2023. Samples were processed, bacteria responsible for infection were isolated. Further gram - positive organisms screened for inducible clindamycin resistance, vancomycin resistance and Gram - negative organisms for ESBL and MBL resistance as per CLSI guidelines. Results: Out of 88 samples analysed, 80 (90%) yielded growth. Organisms isolated were Staphylococcus aureus (63.8%), Escherichia coli (17.5%), Acinetobacter species (8.8%), Klebsiella species (5%), Enterococcus species (2.5%) and Enterobacter species (2.5%). Among 10 MDR E. coli isolates 30% were ESBL and 10% were MBL producers. In Acinetobacter species isolates 57% were ESBL producers and 28% were MBL producers and was more sensitive to aminoglycosides. Conclusion: This study explores recent trends in antimicrobial resistance patterns and therapeutic strategies for managing LSCS surgical site infections. Conducted on 88 patients over 10 months, the research identifies key microbial agents responsible for infections, focusing on Gram positive and multidrug - resistant Gram - negative organisms. Findings emphasize the rising prevalence of methicillin - resistant staphylococcus aureus and extended spectrum beta - lactamase producing pathogens. The study underscores the importance of targeted therapeutic approaches and stringent infection control measures to mitigate antimicrobial resistance and improve maternal outcomes.
Keywords: LSCS surgical site infections, antimicrobial resistance, Staphylococcus aureus, multidrug - resistant pathogens, infection control
Edition: Volume 14 Issue 1, January 2025
Pages: 948 - 951
DOI: https://www.doi.org/10.21275/MR25121105107
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