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Comparative Studies | Medical Surgical | India | Volume 13 Issue 10, October 2024 | Popularity: 5.4 / 10

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A Prospective Comparative Study of Topical Sucralfate 7% vs Silver Sulfadiazine 1% in the Management of Second Degree Burns

Aashish S. Pawar, G. Prabhu, Senthilnathan, K. Ravichandran

Abstract: Background: Burns are a major cause of morbidity and psychological distress, particularly prevalent and severe in developing countries. They can lead to significant economic burdens and complications such as infections, delayed healing, and scarring. While silver sulfadiazine has been a common topical treatment, new alternatives like topical sucralfate are showing potential in improving wound healing and infection control. This study aims to compare the effectiveness of 7% topical sucralfate versus 1% silver sulfadiazine in treating second - degree burns, focusing on healing rate, wound size reduction, infection rates, and overall cosmetic outcomes. Materials and Methods: A prospective comparative study was conducted at AVMCH from September 2022 to July 2024. Seventy - six patients with second - degree burns were included in the study and divided into two groups based on convenience sampling: one treated with 7% topical sucralfate and the other with 1% silver sulfadiazine. Both groups were similar in age, gender, burn site, and physical characteristics. Wound assessments, including size measurements and infection rates, were performed on days 0, 3, 7, and 21. Statistical analyses were conducted using SPSS version 28, with significance set at p<0.05. Results: The sucralfate group demonstrated a significantly greater reduction in mean wound size compared to the silver sulfadiazine group. By day 21, 86.8% of patients in the sucralfate group achieved complete healing, compared to 68.4% in the silver sulfadiazine group. Furthermore, the sucralfate group had a significantly lower incidence of infection, indicating superior infection control (p<0.05). Conclusion: Topical sucralfate 7% is more effective than silver sulfadiazine 1% in managing second - degree burns, providing better outcomes in wound contraction, healing rate, and infection prevention. Sucralfate shows promise as an alternative treatment for burns, potentially improving patient outcomes and reducing complications associated with burn injuries.

Keywords: Burns, Sucralfate, Wound Healing, Silver Sulfadiazine, Infection Control, convenience sampling

Edition: Volume 13 Issue 10, October 2024

Pages: 1072 - 1074

DOI: https://www.doi.org/10.21275/MR24803135352

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