International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Comparative Studies | Surgery | India | Volume 12 Issue 9, September 2023


A Comparative Study of Conservative vs. Percutaneous Needle Aspiration of Liver Abscess based on Liquefaction

Dr. P. Bhagyalakshmi | Dr. V. Mahidha Reddy | Dr. Venkataharish | Dr. A. Murali | Dr. Bharath [12] | Dr. Ravikiran [2]


Abstract: Introduction: Pyogenic liver abscess (PLA) may be defined as solitary or multiple collections of pus within the liver, the result of bacterial infection. Incidence of pyogenic liver abscess is 2.3/1,00,000. {2} Approximately one tenth of the world population is believed to be infected with E. histolytica, with 100,000 deaths worldwide each year due to invasive amebiasis. Materials and Methods: This study was conducted in department of general surgery, Narayana Medical College, Nellore. Duration of study-August 2018 to July 2022. Total no. of patients-140 patients. Analysis: The results of the study were analyzed using SPSS software v 25.0. P-value was calculated using chi-square test. P-value <0.05 was considered significant. Procedures: Conservative treatment: Intra venous 3rd generation cephalosporins. (1gm BD) and metronidazole therapy (500 mg TID) along with analgesics and antacids were given. Percutaneous needle aspiration was done under ultrasound guidance. Under local anesthesia. Follow up: Patients were followed in general surgery OPD for 1 year and their condition was reassessed clinically and radiologically. Totally 120 patients, 60 in each group completed follow-up period of 1 year. During follow up, a total of 20 patients were dropped (10 in each group) due to non-compliance to treatment (16) and death (4). Death of the patients was due to old age and comorbidities-mainly renal failure. Discussion: In Group-A, more patients were satisfied with conservative treatment than percutaneous needle aspiration. In Group-B, more patients were satisfied with percutaneous needle aspiration than conservative treatment. Conclusion: In group B, very few patients responded to conservative management and almost all patients responded to percutaneous treatment. Even though, there was post procedure pain in percutaneous needle aspiration group, it was less when compared with pre-procedure pain related to liver abscess.


Keywords: Pyogenic liver abscess, conservative treatment, percutaneous needle aspiration, management, comparative study


Edition: Volume 12 Issue 9, September 2023,


Pages: 1069 - 1071


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