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Doctoral Thesis | Medical Surgical | India | Volume 12 Issue 8, August 2023

Study of Clinical Evaluation of Glaucoma with Anterior Segment OCT (Optical Coherence Tomography) and Optic Nerve Head OCT (Optical Coherence Tomography)

Dr. Avanish Kumar Singh | Dr. Anjali D Patil | Dr. Vijay Hari Karambelkar

Abstract: Glaucoma is an ocular disease which of chronic and progressive nature which leads to optic neuropathy caused due to certain group of optic conditions which can cause damage to the nerve and further lead to loss of vision. Increased intraocular pressure remains the most common cause of glaucoma. A gradual and sustained rise in the intraocular pressure can occur because of increased formation of aqueous humour, problem in the drainage of the aqueous humour or it can also happen due to increased episcleral venous pressure. OCT imaging technique enables noncontact, non - invasive imaging of the anterior eye along with features of human retina including fovea and optic disc. Though imaging up 2 to 3 mm deep can be achieved in most tissues. This is similar to conventional biopsy and histology. Imaging depth of OCT is more than 10 to 100 times finer than the standard clinical ultrasound. OCT has been applied in vitro to image arterial pathology and can differentiate plaque morphology. Aim: To study the anterior segment OCT and optic nerve head OCT findings in glaucoma. Material and methods: The study was conducted at KRISHNA INSTITIUE OF MEDICAL SCIENCES ON 45 patients who inclusive fulfill the criteria?s were chosen as study subjects. Patients suspected with Glaucoma coming to the OPD at Krishna Hospital, Karad were included in the study. All the patients underwent AS - OCT and RNFL under various modalities and data were collected. The collected data was compiled in Microsoft Excel 2010. Data was analyzed using SPSS (Statistical Programme for Social Sciences) software 21 version, OpenEpi Software Version 2.3. Results: There were 45 patients in my study who were included in it. Out of this, 67% (30) of the participants were men, and 33% (15) were women. The most affected age group was determined to be 61?70 years old with 36% incidence. It was discovered that the AOD and TISA declined linearly with increasing pupil size in 78.2% of instances. On assessment of the laterality, 33% were involved with the right side and 67% with the left side. Three patients exhibited trabecular iris angles less than 25 degrees on AS - OCT, while the other patients all had angles greater than 25 degrees. we found that most of the patients had CCT 500 m It was also found that 6 patients age group 20 - 40 years with IOP range from 22 - 30 mmhg had CCT above 550 m and corrected was found to be effective. . Of these 6 patients, all had CDR values more than 0.6, but NRR was healthy. A P value of 0.001 was reported for the macular thickness, which was 276 26 (223 - 346) Because there hasn't been much research on AS - OCT and RNFL in relation to glaucoma, this work will be highly helpful for future references. Conclusion: Combining both aspects of the anterior and posterior segment which helps in early diagnosis of glaucoma and patient can start on treatment, as well as keeping track on progress, OCT imaging technique allows noncontact, non - invasive imaging of the anterior eye along with features of the human retina including fovea and optic disc and gives quantitative analysis, requiring minimal skills and taking less time to operate.

Keywords: Glaucoma, OCT, Optical Coherence Tomography, Optic Nerve Head

Edition: Volume 12 Issue 8, August 2023,

Pages: 627 - 632