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Research Paper | Obstetrics and Gynecology | India | Volume 12 Issue 5, May 2023
A Study on Hydatidiform Mole
Dr. Bhakti V Kalyankar | Dr. Vijay Y Kalyankar | Dr. Shrinivas N Gadappa | Dr. Harshitha S | Dr. Ishwarya M
Abstract: Introduction: The pre malignant form of gestational trophoblastic neoplasia is known as molar pregnancy (hydatidiform mole). Hydatidiform mole includes complete mole and partial mole. Aims And Objectives To calculate incidence, socio - demographics, clinical profile of hydatidiform mole. of hydatidiform mole and study pattern of normalization of serum ? hCG levels. Methodology: This study was a Prospective observational study conducted from September 2019 to October 2021 (2 years). Results: The incidence of the hydatidiform mole during the study period in the institution was 1.58 per 1000 pregnancies. Apart from history of amenorrhea, vaginal bleeding (60%) was the most common presenting symptom.16 (32%) cases did not have any symptoms and were diagnosed on routine antenatal ultra sonography. (36%) of the study group were Primigravida.80% (40) had ultrasonographic finding of complete mole and 20 % had partial mole. Majority 68 % (34) presented in the first trimester (<12 weeks). In the present study majority (52%) were of the blood group B positive. The mean time taken was 7.62 ? 2.49 weeks to attain normal serum ? hCG levels from the pre evacuation values. Histopathology gave definitive diagnosis in all cases. Prevalence of Gestational trophoblastic neoplasia in our study was 0.06. Conclusion: History of amenorrhoea with bleeding per vaginum and size of uterus more than period of amenorrhoea should raise suspicion of H. mole though asymptomatic cases do exist. Obstetric ultrasonography and raised serum ? hCG are diagnostic for Hydatidiform mole. Time taken for ? hCG levels to drop down to normal was more in cases of complete mole than partial mole.
Keywords: ? hCG, Molar pregnancy, Complete Mole, Partial Mole
Edition: Volume 12 Issue 5, May 2023,
Pages: 776 - 781