Correlation of Diabetic Macular Edema (DME) with Glycosylated Haemoglobin

Dr. Deba Pratim Das, Dr. Moushumi Majumder

Abstract: Purpose: To correlate between central macular thickness measured by OCT and HbA1c in diabetics. Method: Hospital based observational study of 65 patients of Diabetic Retinopathy with and without DME. Dilated fundus examination was done and cases identified with DME were evaluated by Optical Coherence Tomography (OCT) of macula, which were then compared with Glycosylated Haemoglobin (HbA1c) level. Results: 65 eyes of 65 patients were included in the study. The HbA1c level (8 or over) showed a significant (p <0.001) and positive association with macular thickness in OCT. Conclusion: So, close monitoring of HbA1c level is necessary for the management and also for knowing the prognosis of the cases of DME.

Keywords: Diabetic macular edema, glycosylated haemoglobin, optical coherence tomography