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Doctoral Thesis | Food & Nutrition | India | Volume 12 Issue 10, October 2023
Marine Grass Boone to Diabetes
S K. Ruksana | Dr. A. Jyothi [2]
Abstract: The global population will be increasing day by day and suffering with non communicable diseases especially Diabetes mellitus which is related to faulty dietary habits include low fiber intake and high intake of carbohydrates and lack of intake of multi nutrients. Compared to other risk factors, obesity and overweight are the most significant risk factors for diabetes. During 2017, we were conducted a study on, Obesity is a predisposing factor of diabetes mellitus, the results shows majority of the subjects (88%) are obese because of their faulty dietary patterns. Keeping this in view, which are abundant to human consumption, there as interest in looking for new bioactive compounds to treat this disease, including metabolites of marine origin. The present study aimed to check the anti diabetic activity of HALODULE UNINERVIS powder in streptozocin induced diabetic rats. It is a seagrass that is high in polyphenols, magnesium, zinc, iron, and dietary fiber. Low in carbohydrates. Divided the wistar rats into five groups include normal control, diabetes control, supplementation of powder 50mg/kg.b.wt, 150mg/kg.b.wt and 250mg/kg.b.wt for 20 days. Anti diabetic effect supplementation was slightly decreased at the 10 hour. The final results shown 35percent observed on the 20th day by 100mg/kg administration. 54percent reduction of glucose level in the 20th day administration at dose level of 150mg/kg. 250mg/kg supplementation is more effective were observed 63percent on the 20th day. Higher dosage of supplementation will be more effective compare to other doses. Additionally it was observed there is no toxicity of this grass. So it can be used for human consumption to control blood glucose levels in diabetes.
Keywords: Halodule uninervis, diabetes mellitus, anti-diabetic properties, marine-derived compounds, blood glucose levels
Edition: Volume 12 Issue 10, October 2023,
Pages: 555 - 556