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Research Paper | Pharmacology and Toxicology | Iraq | Volume 11 Issue 8, August 2022

The Histological Effects of Volatile Oil and Seeds of Bitter Fennel (Foeniculum Vulgar-var. vulgare) in Hyperlipidemic Rats

Nada Nasser Faris

Abstract: The experiment conducted during 2019/2020 in the laboratory of the college of Agriculture / Basrah University. To study the histological effects of volatile oil and seeds of bitter fennel (Foeniculum vulgare var. vulgare) in laboratory rats. Rats were divided into four major groups, control, hyperlipidemic and hyperlipidemic treated with volatile oil of bitter fennel at doses 40 mg. kg-1 b. w. and hyperlipidemic treated with grind seed at dose 1000 mg. kg-1 b. w. duration three weeks. Hypolipidemia was developed by diet contained 1% cholesterol for 21 days. The results showed no changes in control (normal rats) and the tissue remain within normal limits. Whereas, the rat treated with cholesterol only, illustrate clear morbid changes. While liver and kidney in rats treated with cholesterol then with essential oil and grind seed of bitter fennel duration three weeks, showed amelioration in histological picture compared with group treated with cholesterol only (hyperlipidemic group).

Keywords: Cholesterol; Bitter fennel; Hyperlipidemia

Edition: Volume 11 Issue 8, August 2022,

Pages: 950 - 953