PRES Masquerading as CVA or Meningitis

Dr. Ritu Gupta, Dr. Sandeep Singh, Dr. Sushma Choudhary, Dr. Vanisha Jhawar

Abstract: PRES is a neurological disorder which is characterised by acute emergency presentation, which include visual disturbances, headache, vomiting, seizures and altered consciousness. The exact pathophysiology of PRES has not been completely explained, but hypertension and endothelial injury seem to be almost always present. Vasoconstriction resulting in vasogenic and cytotoxic edema is suspected to be responsible for the clinical symptoms as well as the neuro - radiological presentation. We are presenting cases of PREE syndrome who were having no previous history of Systolic hypertension, or fever but presented with hypertension and altered sensorium. A 58 yr old female presented with complaints of severe headache, vomiting followed by abnormal body movements and altered sensorium for about 1 day. Her routine investigation like CBC shows Pancytopenia and LFT, RFT appears to be normal. She is k/c/o Aplastic anemia and is on Tab Cyclosporine since 1 month. Another patient, a 29 yr old male presented with complaints of vomiting and loss blurring of vision. RFT was deranged and Urine routine examination shows pus cells and RBC. ASO titre came positive which s/o Post infective glomerulonephritis. CE- MRI brain of both patients shows focal areas of hyperintensity scattered in white matter, sign of PRES. These patients respond symptomatically on antihypertensive and MRI changes revert back to normal after treatment

Keywords: PRES, Posterior reversible encephalopathy syndrome, CBC, Complete blood count, RFT, Renal function test, LFT, Liver function test.

How to Cite?: Dr. Ritu Gupta, Dr. Sandeep Singh, Dr. Sushma Choudhary, Dr. Vanisha Jhawar, "PRES Masquerading as CVA or Meningitis", Volume 13 Issue 5, May 2024, International Journal of Science and Research (IJSR), Pages: 318-321, https://www.ijsr.net/getabstract.php?paperid=ES24501162206, DOI: https://dx.doi.org/10.21275/ES24501162206