Amsan Variant of Guillain-Barresyndrome: A Case Report

Anzon John

Abstract: Guillain- Barré syndrome (GBS) is a rare and potentially life-threatening medical condition resulting from an individual’s immune system’s attack on the peripheral nerves. It is the result of an auto-immune response leading to axonal degeneration or demyelination. Acute motor and sensory axonal neuropathy (AMSAN) is a variant of GBS with the poorest prognosis. It is characterized by rapid-onset motor weakness, loss of deep tendon reflexes and sensory changes. Immunotherapy is considered a standard treatment for GBS. Here, the reported case is of AMSAN variant of GBS in a 42-year-old patient, who developed bilateral facial nerve palsy and treated with intravenous immunoglobulin (IVIg).

Keywords: immune system, deep-tendon reflexes, lower and upper limbs, muscle movement